Clinical Trials

NCT IdNCT04833387
TitlePD-1 Antibody Following Preoperative Chemoradiotherapy for Locally Advanced pMMR/MSS Rectal Cancer
ConditionLynch Syndrome
OrganizationSun Yat-sen University
Sponsor/CollaboratorsSun Yat-sen University
Older Adult
Location (with distance)
  • 651 Dongfeng Road East, Guangzhou, 510060 , China
DescriptionIn this open-label phase II study, patients will be scheduled for neoadjuvant treatment with PD-1 antibody following preoperative Chemoradiotherapy with capecitabine for pMMR/MSS rectal cancer staged as locally advanced (cT3-T4N+/-M0 for rectal cancer). This treatment will be given during the window period until surgical resection of the tumor.