Clinical Trials

NCT IdNCT04107402
TitlePLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock
ConditionSeptic Shock
StudyTypeInterventional
OrganizationCliniques universitaires Saint-Luc- Université Catholique de Louvain
Sponsor/CollaboratorsCliniques universitaires Saint-Luc- Université Catholique de Louvain
StatusRecruiting
GenderAll
AgeGroupAdult
Older Adult
Location (with distance)
  • Cliniques Universitaires St Luc, Bruxelles, 1200 , Belgium
DescriptionKnowing the dramatic increase in thrombin generation during sepsis, our research hypothesis is that AMPK-induced ACC phosphorylation in platelets is increased and that this might modulate platelets metabolism and more particularly platelets inflammatory mediators content, coming from AA and lipids.